Kardia-3

Enrolling, Hypertension
The purpose of this study is to evaluate the effect of zilebesiran as add-on therapy in patients with high cardiovascular risk and…

MUIR-3

Enrolling, High Triglyceride
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with hypertriglyceridemia…

Redefine-3

Enrolling, Weight Loss
This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with…

Shasta-4

Enrolling, High Triglyceride
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with severe…

BalanceD-HF

Enrolling, Heart Failure
The purpose of this study is to investigate the effect of balcinrenone/dapagliflozin compared with dapagliflozin, on the risk of CV death…

Triumph

Enrolling, Weight Loss
The main purpose of this study is to evaluate the efficacy and safety of retatrutide once weekly in participants with obesity and…

Tharros

Enrolling, COPD
THARROS is the first-ever prospective trial to investigate the potential of an inhaled triple therapy to reduce cardiopulmonary events, a…

Acclaim

Enrolling, Lipoprotein (a)
The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a…

Hermes

Enrolling, Heart Failure
This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will…

Merck Cholesterol

Enrolling, Cholesterol
The goal of this study is to evaluate the efficacy, safety, and tolerability of MK-0616 in adult participants with hypercholesterolemia. The…

Power HF

Enrolling, Heart Failure
The purpose of this study is to evaluate the efficacy of the medication JTT-861 administered for 12 weeks in subjects with heart failure…

Achieve-4-GZGS

Enrolling, Diabetes
The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type…
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